ࡱ> rtopq Abjbjhh -D__J+8$ 0`!p")")")"#.2#F# _______cf_QR###R#R#_)")"_111R# )")"_1R#_11nOaRQl.:P _`00`Pg1(g@aRaR.gT R#R#1R#R#R#R#R#__1R#R#R#0`R#R#R#R#gR#R#R#R#R#R#R#R#R#Y ]:  CURRICULUM VITAE Douglas B. Matthews April 2024 Office Address Department of Psychology Vloge 270 Hibbard Hall Eau Claire WI 54702  HYPERLINK "mailto:matthedb@uwec.edu" matthedb@uwec.edu laboratory website: http://wiaddictionresearc.wix.com/wiaddictionresearch PERSONAL INFORMATION Date of birth: October 10, 1968 Marital Status: Married, three children EDUCATION 1999 Post-doctoral Research Fellow Laboratory of Dr. A. Leslie Morrow University of North Carolina-Center for Alcohol Studies 1996 Ph. D., Psychology Miami University Dr. Phillip J. Best, advisor 1994 M.A., Psychology Miami University 1991 B.S., Psychology/Biology (cum laude) Southwest Missouri State University PROFESSIONAL MEMBERSHIPS Research Society on Alcoholism International Society for Biomedical Research on Alcoholism Society for Neuroscience PROFESSIONAL EXPERIENCE 2014 Present Full Professor, with tenure University of Wisconsin Eau Claire Department of Psychology 2014 2020 Chair University of Wisconsin Eau Claire Department of Psychology 2012 - 2014 Head of Department Nanyang Technological University, Singapore Division of Psychology 2009 2014 Associate Professor, with tenure Nanyang Technological University, Singapore Division of Psychology 2009 2015 Research Scientist Baylor University Department of Psychology and Neuroscience 2007 2009 Associate Professor, with tenure Baylor University Department of Psychology and Neuroscience 2007 Visiting Associate Professor National University of Singapore 2003 2007 Director Tennessee Center for Addiction Research 2003 2007 Board of Directors Tennessee Biotechnology Association University of Memphis Representative 2003 2007 Associate Professor, with tenure Department of Psychology The University of Memphis 2003 2007 Adjunct Assistant Professor Anatomy and Neurobiology University of Tennessee Health Science Center 2001 2007 Feinstone Center for Genomic Research Member The University of Memphis 1999 2003 Assistant Professor Department of Psychology The University of Memphis 1996-1999 Postdoctoral Research Fellow (Laboratory Manager) University of North Carolina-Center for Alcohol Studies 1992-1996 Graduate Research Assistant Miami University Laboratory of Dr. Phillip J. Best 1992-1995 Graduate Teaching Assistant Miami University Graduate Teaching Assistant University of Memphis 1989-1991 Undergraduate Tutor, Statistics Southwest Missouri State University ADMINISTRATIVE EXPERIENCE Chair, Department of Psychology, University of Wisconsin Eau Claire (July 2014 to June, 2020) Core Responsibility: Oversee and direct the functioning of the Psychology Department (700+ majors, 250+ minors, 30+ graduate students) at Vlog. Direct oversight of all faculty, graduate students and staff. Plan, oversee and manage departmental budget. Direct tenure and promotion applications of faculty and implement aggressive expansion plans for the division. Accomplishments: Year 1 Developed diversity committee for department. Developed social media strategy for department. Obtained over 950 sq ft of new laboratory space. Started department seminar series. Obtained office space for departmental undergraduate tutors Successfully led department through 5 year review which included drafting departmental self-study and internal and external reviews. Implemented faculty review procedure Increased summer enrollment by 23.8% Year 2 Facilitated department in writing mission statement Facilitated opening of new behavioral neuroscience laboratory Worked with faculty in the Graduate School Psychology program to incorporate greater student credit hour production by opening selected classes to undergraduate enrollment. Worked with faculty in Behavior Analysis to broaden the program to include additional pathways to degree thereby increasing enrollment in the major. Worked with curriculum committee and math department to transition statistic course to math department freeing instruction staff in Psychology. Increased Winterim enrollment by 58%. Facilitated the formation of and the unanimous approval of a new departmental mission statement. Participated in development of Neuroscience minor in Biology Department Year 3 Increased summer enrollment by 29.4% Successfully obtained and hired new tenure track line in Clinical Psychology (focus Cultural/Cross Culture Psychology) Facilitated update of Department website with the University administration. Increased Winterim enrollment by 14.4% Facilitated hiring of Departments first post doctoral research scholar Facilitated completion of behavioral neuroscience research space Facilitated approval of new departmental major in neuroscience Year 4 Increased foundation donations to the department by 77% over previous year. Increased summer enrollment by 7%. Successfully obtained and hired new tenure track line in Social Psychology (focus Cultural/Cross Culture Psychology) Facilitated development and implementation of comprehensive major in neuroscience. Major involves six departments from two colleges at Vlog. Year 5 Gained new tenure track faculty line in Educational Psychology. Obtained 500 sq ft of new laboratory space and facilitated opening of new laboratory focused on Black Psychology Facilitated remodel of laboratory space and opened new laboratory focused on the Psychology of Prejudice. Successfully obtained and hired new tenure track line in Educational Psychology. Increased winterim enrollment by 29%. Year 6 Facilitated opening of laboratory in Educational Psychology Increased percentage of Faculty of Color in Psychology from 0% (2014) to 11.1% (2019). Facilitated development of Student Success Plan to enhance enrollment and student retention. Faculty Workload Workgroup, Chair (2018-2020; appointed by Provost) Core responsibility: To study and propose solutions to equate faculty workload across the university. Chancellors Cabinet (2017-2019; appointed by Chancellor) Core responsibility: To provide candid and constructive feedback to Chancellor surrounding issues important to the Vlog academic community specifically and higher education in general. Science Building Designed Team (Fall, 2017 to Current ; appointed by vice-provost). Core responsibility: To provide insight and functional analysis of development of new science building. Effort resulted in new science building ($256 million) being included in UW Regents budget request. Academic Master Plan Implementation Team (Fall, 2015 to 2017; appointed by Provost) Core responsibility: To articulate a clear set of considerations within which members of the campus community can vet ideas, guide behaviors, and make decisions. The Academic Master Plan will focus on the articulation of our collective conscience and foster its application across all decision making on campus. An articulation of these considerations will allow the institution to maintain a consistent yet flexible path forward. The Academic Master Plan will be the collective conscience guiding all of us in our decision making and behavior in the next five years. Academic Workload Rapid Action Task Force (Spring, 2015; appointed by Chancellor) Core responsibility: Redesign expectations for teaching, scholarship, service and advising to accommodate the anticipated $300 million budget cut to the state of Wisconsin university system. Produced written report for University Executive Committee, presented report to various university stakeholders. University Assessment Committee, University of Wisconsin - Eau Claire (May 2015-2017). Head of Division, Psychology, Nanyang Technological University Singapore (Oct 2012 to July 2014) Core Responsibility: Oversee and direct the functioning of the Psychology Division at Nanyang Technological University. Direct oversight of all faculty, post doctoral researchers, graduate students and staff. Plan, oversee and manage divisional budget. Direct tenure and promotion applications of faculty and implement aggressive expansion plans for the division. Accomplishments: Successfully hired eight faculty at junior and midlevel rank. Successfully proposed three new faculty hires. Support faculty scholarship including greater than 50 publications, 1,300 citations and +4.5 million SGD in grant funding (ongoing) in first year. Exceed target intake for freshman by +58% in first year. Developed and implemented second major program of Psychology and Biological Sciences in first year. School of Humanities and Social Sciences, Management Committee, Nanyang Technological University Singapore (Oct 2012 to present) Core Responsibility: Provide support and oversight for division comprising HSS (divisions include Psychology, Sociology, English, Chinese, Philosophy, History, Economics, Global Policy, Linguistics). Evaluate program performance and provide information as it relates to strategic planning of the School. Accomplishments: Successfully met HSS student intake for year 2013-2014. Developed branding strategy for HSS 10 year anniversary. GRANTS National Institute on Alcohol Abuse and Alcoholism: National Research Service Award (1 F31 AA05414-01A1). Prenatal Ethanol: Place Cell and Spatial Memory Effects. Principal Investigator $13,008.00 total cost National Institute on Alcohol Abuse and Alcoholism: National Research Service Award (1 F32-AA05519-01). GABAergic Adaptations to Ethanol Self-administration. Principal Investigator $56,336.00 total cost Alcoholic Beverage Medical Research Foundation (06/01/00 05/30/02) The neuroactive steroid 3(-hydroxy-5(-pregnan-20-one modulates ethanol-induced decreases in spatial cognitive processing. Principal Investigator $80,000.00 total cost University of Memphis Faculty Award (06/01/00 05/30/01) Effects of the neuroactive steroid 3[a]-hydroxy-5[a]-pregnan-20-one on spatial cognitive processing in the rat. Principal Investigator $4,000.00 National Institute of Health (9/25/00 - 8/30/05) (1 U01 MH61971-01) Targeted mutagenesis of the mouse genome and neural phenotype Principal Investigator Dan Goldwitz, UT-Memphis Medical Center $12,774,513.00 total costs Investigator and Co-Director of Alcohol Core $1,277,515.00 Total cost to the University of Memphis University of Memphis Faculty Award (06/01/01-05/30/02) Effects of de novo blockade of the neuroactive steroid 3[a]-hydroxy-5[a]-pregnan-20-one on ethanol induced spatial working memory impairments. Principal Investigator $4,000.00 National Institute on Alcoholism and Alcohol Abuse (02/01/02 1/31/08) INIA: Systems Mechanism in Alcohol-Stress Interaction Principal Investigator $1,378,312.00 total cost University of Tennessee Health Science Center (01/01/04 12/31/04) Mouse Husbandry Principal Investigator $15,000.00 University of Memphis Faculty Award ((7/01/04 6/30/05) The effect of ethanol consumption on physiology and gambling behavior: identifying mechanisms to encourage effective self-regulation. Principal Investigator $6,000.00 National Institute on Alcoholism and Alcohol Abuse (9/18/04 9/17/08) GABAa receptor g[2] knockout: ethanol and spatial memory Principal Investigator $381,750 National Institute on Alcoholism and Alcohol Abuse (11/01/04-10/31/09) Ethanol mechanisms in GABAAR gene targeted mice Subcontract from U of Pittsburgh PI on Subcontract $278,456 Baylor/Waco Foundation (11/23/08-12/31/09) BSAD Educational Grant Principal Investigator $19,000 Nanyang Technological University (1/1/10 to 12/31/12) Investigations into the interaction of alcohol and stress on hippocampal dependent memory across the lifespan in rats Principal Investigator $99,999.00 SGD ($72,128.44 USD conversion 11/24/09) Nanyang Technological University (1/1/10 to 12/31/10) The effects of presence of peers on estimated standard drink size in Singapore college students Principal Investigator $5,000 SGD ($3570.15 USD conversion on 3/10/10) Ministry of Social and Family Development (4/1/13 to 7/1/14) Qualitative study of the behaviours and attitudes of youths towards gambling and the casino Co-Principal Investigator $70,000 ($56,310.80 USD conversion on 3/28/13) Nanyang Technological University (1/1/2014 to 12/1/2014) Alcohol and the brain Principal Investigator $35,000 ($27,540 USD conversion on 2/4/2014) University of Wisconsin Eau Claire Faculty Award (5/2015) The effect of chronic ethanol in aged rats. Principal Investigator $4,500.00 University of Wisconsin Eau Claire Faculty Award. (5/2015) ORSP and College of Arts & Sciences Modeling late onset alcoholism with rats. Principal Investigator $15,000.00 University of Wisconsin Eau Claire Faculty Research Award (8/2018) ORSP Research training via Duke University Principal Investigator $1,100.00 Mayo Health Care-Vlog Research and Innovation Council (5/1/2019 4/30/2021) Impact of Binge-like Alcohol Exposure During Adolescents Across the Lifespan: Behavior to Neurobiology Principal Investigator $174,761.00 University of Wisconsin Eau Claire Faculty Research Award (11/2019) ORSP Anxiety across the lifespan in rats Principal Investigator $2,800.00 University of Wisconsin Eau Claire Summer Research Award (4/27/20) ORSP Impact of F639A mutation on spatial and non-spatial learning Principal Investigator $7,500.00 Mayo Health Care-Vlog Research and Innovation Council (9/1/2020-8/30/22) Mechanism underlying increased ethanol sensitivity in aged animals Principal Investigator $124,112 Biomedical Innovation Grant Mayo Healthcare $16,800 University of Wisconsin Eau Claire Summer Research Award (4/21/21) Impact of W825A mutation on spatial memory Principal Investigator $10,900.00 Mayo Bioinnovator Grant Mayo Healthcare $11,200.00 University of Wisconsin Eau Claire Effect of W825A mutation on ethanol induced spatial memory $17,200.00 Mayo Health Care Vlog Research Innovation Council (2/1/2023 8/31/2024) Neurobiology Underlying Cognitive Deficits of [d]9-THC and Ethanol Exposure In Aged Rats $107,835 Mayo Bioinnovator Grant Mayo Healthcare $16,200 HONORS Note of appreciation from UW System interim President Tommy Thompson, 2021 Certificate of Recognition TRIO Student Support Services, 2017 and 2018 Fulker Award, Behavior Genetics Association, 2009 for particularly meritorious paper Excellence in Teaching Award, College of Arts & Sciences, University of Memphis, 2005 Participate, Society for Neuroscience Press Conference on the Adolescent Brain, 2003. T.W. Briggs Foundation Excellence in Teaching Award -- Nominated Young Investigator Award Research Society on Alcoholism, 2002 External Reviewer Baylor University Department of Psychology and Neuroscience Early Career Research Award University of Memphis, 2001. Junior Faculty Travel Award American Society for Biochemistry and Molecular Biology Ethanol and Cell Signaling, Oct. 1999. NIAAA Post-doctoral Fellowship (1 F32-AA05519-01), 1998-1999. Neurobiology Training Grant Recipient-UNC-Chapel Hill 1997-1998. NIAAA Pre-doctoral Fellowship (1 F31 AA05414-01A1), 1996. Dissertation Fellowship, Miami University--Psychology, 1995-1996. Research Society on Alcoholism--Junior Investigator Award, June 1997. Research Society on Alcoholism/International Society for Biomedical Research on Alcoholism--Graduate Student Travel Award, June 1996. Jeff Stein Graduate Fellowship, May 1994--$1,000.00. Achievement Awards, Miami University, 5 awards totaling $1,250.00. Abstract selected by the Committee on National Advocacy of the Research Society on Alcoholism for distribution to national news services and media representatives. Capretta Memorial Scholarship for Outstanding Graduate Student in Psychology, April 1996. Letters of Commendation, Miami Psychology Department, 1993, 1994, 1995, 1996. WORKSHOPS Experimental Neurogenetics of the Mouse, 2004 - 2006, Memphis TN Organizer and Faculty 10th Summer School on Behavioral Neurogenetics, August 8-14, 2004, Memphis TN Organizer and Faculty SERVICE External promotion to Associate Professor reviewer North Carolina Central University Department of Neuroscience, 2022 External promotion to Full Professor reviewer West Virginia University Department of Neuroscience, 2020 External tenure and promotion reviewer University of Minnesota Duluth Department of Psychology, 2019 University of Wisconsin Eau Claire Chair of Psychology Department, in charge of budget, hiring, planning, tenure and promotion, 2014 to present Internal review committee, Department of Art and Design, Fall, 207 Nanyang Technological University Head of Division, in charge of budget, hiring, planning, tenure and promotion, 2012 to 2014 Co-Coordinator, New Frontiers in Neuroscience Cluster, NTU 2012 to 2013 Promotion review, school of Humanities and Social Sciences, 2011 External review for Psychology of SIM University, Singapore, 2010 NTU Research Council, Accountancy, Business, Humanities and Social Sciences subcommittee member. 2010 to 2012. Faculty Search Committee, Chair, Nanyang Technological University, 2009. Management Committee, Department of Psychology, Nanyang Technological University, 2009-present. Undergraduate Admissions Committee, Department of Psychology, Nanyang Technological University, 2009-present. University of Memphis Tenure and Promotion Committee member, Dr. Charles Blaha, 2007 Animal Facilities Committee, Chair, 2007 Faculty Advisory Committee: 2001-2005, University of Memphis Personnel Committee: 2002-2003, University of Memphis Undergraduate Curriculum: 1999-2006, University of Memphis Chair, 2002 to 2006 Newsletter Committee: 2001-2006, University of Memphis TEACHING Introduction to Biopsychology. Miami University; University of Memphis; Nanyang Technological University Introduction to Statistics. University of North Carolina Chapel Hill; University of Memphis; Nanyang Technological University; University of Wisconsin - Eau Claire Introduction to Psychology. University of Memphis; Nanyang Technological University, University of Wisconsin Eau Claire Alcohol, Drugs and Behavior. University of Memphis; National University of Singapore; Nanyang Technological University; University of Wisconsin Eau Claire Neurobiology of Learning and Memory. University of Memphis. Literature in Neuroscience, Baylor University Research Methods, Baylor University; Nanyang Technological University Introduction to Neuroscience. University of Wisconsin Eau Claire Sensation and Perception. University of Wisconsin Eau Claire Teaching Workshops Teaching Boost Series: Course Redesign Organization in Canvas Workshop, Summer 2023 Teaching Boost Series: Get Started with Video Creation (Basic) workshop, Summer 2023 Student Success teaching module, Summer 2023 EDITORAL BOARDS: Alcohol Editor-in-Chief, 2024 - present Alcohol, 2008-2023 Alcoholism: Clinical and Experimental Research, 2011-2023 Behavioral Sciences, 2022-present Journal of Addiction, 2012 - 2017 EDITORAL EFFORT: Alcohol and Adolescence, Guest Editor for Special Issue for the journal Alcohol Alcohol and Aging, Guest Editor for Special Issue for the journal Alcohol RESEARCH SERVICE: Executive Committee: Singapore chapter for Society for Neuroscience, 2010 Program Committee Member, Research Society on Alcoholism, 2007 JOURNAL REVIEWER: Journal of Pharmacology and Experimental Therapeutics Hippocampus Neuroscience Pharmacology, Biochemistry & Behavior Neurobiology of Learning and Memory Wadsworth Publishing Neuropharmacology Alcoholism: Clinical and Experimental Research Brain Research Behavioural Brain Research Developmental Brain Research Journal of Neurochemistry European Journal of Neuroscience Genes, Brain and Behavior Alcohol Journal of Proteomic Research Current Biology BMC Anesthesiology Advances in Drug and Alcohol Research Brain Sciences Behavior Sciences GRANT REVIEWER: National Institute on Alcohol and Alcoholism, Ad hoc reviewer for Special Emphasis Committee, ZAA1 JJ (01), 2017 National Institute on Alcohol and Alcoholism, Ad hoc reviewer for Special Emphasis Committee, ZAA1 JJ (08), 2016 AA-4, National Institute on Alcohol and alcoholism, Study Section Ad Hoc member, 2015 National Institute on Alcohol and Alcoholism, Ad hoc reviewer for Special Emphasis Committee, ZAA1 DD (01), 2011 EP4, Nanyang Technological University, Review Member, 2010-2012 AA-4, National Institute on Alcohol and Alcoholism, Study Section Member 2008-2009. Neuroscience Special Emphasis Section, NIAAA, NIH 2007. AA-1, National Institute on Alcohol and Alcoholism, Study Section Member 2007. The North Carolina Biotechnology Center, Institutional Development Grant, 2007. National Center for Research Resources, Minority Center Review, Florida A&M University, 2007. National Institute on Alcohol and Alcoholism, Ad hoc reviewer for SEP, neuroscience, 2007. United States Army Medical Research and Materiel Command reviewer (2006, 2007). National Institute on Alcohol and Alcoholism, Ad hoc reviewer for AA1(April and October), DD60, and DD80 2006. Interactive Neuroscience Initiative on Alcoholism, Pilot Project Grant Reviewer, 2003. Center of Excellence External Reviewer - U.S. Army Medical Research and Materiel Command Review of Center from the Ernest Gallo Clinic and Research Center entitled "Translational Center for the Study of Alcoholism and Substance Abuse, 2003, 2005. Scientific Review Board Institute for the Study of Aging 2002-2005 Wellcome Trust Foundation 2003, 2005 PEER REVIEWED PUBLICATIONS Google scholar citations 7477 Google scholar h-index 41 Google scholar i10-index 70 Matthews, D.B. & Best, P.J. (1995). Fimbria/fornix lesions facilitate the learning of a non-spatial response task. Psychonomic Bulletin & Review, 2(1), 113-116. Matthews, D.B., Simson, P.E. & Best, P.J. (1995). Acute ethanol impairs the use of spatial memory but not the use of stimulus/response memory in the rat. Alcoholism: Clinical and Experimental Research, 19(4), 902-909. Matthews, D.B., Simson, P.E. & Best, P.J. (1995). Impaired spatial memory in rats after acute ethanol exposure. Alcoholism: Clinical and Experimental Research, 19(4), Highlights. Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Ethanol alters the spatial processing of hippocampal place cells: a mechanism for impaired navigation when intoxicated. Alcoholism: Clinical and Experimental Research, 20(2), 404-407. Matthews, D.B., Best, P.J., White, A.M., Vandergriff, J. & Simson, P.E., (1996). Ethanol impairs spatial cognitive processing: new behavioral and electrophysiological findings. Current Directions in Psychological Science, 5(4), 111-115. Matthews, D.B. & Best, P.J. (1997). Evidence for the flexible use of spatial knowledge in the rat. Psychobiology, 25(4), 294-302. Matthews, D.B., Devaud, L.L., Fritschy, J.M., Sieghart, W. & Morrow, A.L. (1998). Differential regulation of GABAA receptor gene expression by ethanol in the rat hippocampus vs. cerebral cortex. Journal of Neurochemistry, 70, 1160-1166. Matthews, D.B. & Simson, P.E. (1998). Prenatal exposure to ethanol disrupts spatial memory: effect of the training-testing delay period. Physiology & Behavior, 64(1), 63-67. Grobin, A.C., Matthews, D.B., Devaud, L.L. & Morrow, A.L. (1998). The role of GABAA receptors in the acute and chronic effects of ethanol. Psychopharmacology, 139(1/2), 2-19. Matthews, D.B. & Uhler-Dietz B. (1998). The black sheep effect: how positive and negative advertisements affect voters perceptions of the sponsor of the advertisement. Journal of Applied Social Psychology, 28, 1902-1914. Matthews, D.B., Illgen, M.A., White, A.M. & Best, P.J. (1999). Acute ethanol administration impairs spatial performance while facilitating non-spatial performance in rats. Neurobiology of Learning and Memory, 72, 169-179. Davaud, L. L., Matthews, D. B. & Morrow, A. L. (1999). Gender impacts behavioral and neurochemical adaptations in ethanol dependent rats. Pharmacology, Biochemistry & Behavior. 64, 841-849. Morrow, A.L., Janis, G.L., Van Doren, M.J., Matthews, D.B., Samson, H.H., Janis, P. & Grant, K.A. (1999). Neurosteroids mediate pharmacological effects of ethanol: A new mechanism of ethanol action? Alcoholism: Clinical and Experimental Research, 23, 1933-1940. VanDoren, M.J., Matthews, D.B., Janis, G.C., Grobin, A.C., Devaud, L.L & Morrow, A.L. (2000). Neuroactive steroid 3(-hydroxy-5(-Pregnan-20-one modulates behavioral and electrophysiological actions of ethanol. Journal of Neuroscience, 20, 1982-1989. Matthews, D.B. & Morrow, A.L. (2000). The effects of acute and chronic ethanol exposure on spatial cognitive processing and hippocampal function in the rat. Hippocampus, 10, 122-130. White, A.M., Matthews, D.B. & Best, P.J. (2000). Ethanol, memory and hippocampal function: A review of recent findings. Hippocampus, 10, 88-93. Matthews, D.B. (2000). Ethanol and the hippocampal system: behavior to molecular biology. Hippocampus, 10, 87. Matthews, D.B, Kralic, J. E., Devaud, L.L., Fritschy, J.M. & Morrow, A.L. (2000). Chronic blockade of N-methyl-D-aspartate receptors alters (-Aminobutyric acid type A receptor gene expression and function in the rat. Journal of Neurochemistry, 74, 1522-1528. Kampov-Polevoy, A.B, Matthews, D.B., Gause, L., Morrow, A.L. & Overstreet, D.H. (2000). Development of physical dependence upon alcohol in p rats: changes in seizure thresholds, anxiety and patterns of alcohol drinking. Alcoholism: Clinical and Experimental Research, 24, 278-284. Matthews, D.B., Criswell, H.E., Grobin, A.C. & Morrow, A.L. (2000). Chronic ethanol consumption alters recovery of spontaneously active medial septal/diagonal band of Broca neurons from GABA-microiontophoresis. Alcoholism: Clinical and Experimental Research, 24, 1427-1432. Matthews, D.B., Overstreet, D.H., Rezvani, A.H., Devaud, L.L. & Morrow, A.L. (2001). Comparisons of sweetened ethanol solutions on ethanol self-administration and blood ethanol levels. Pharmacology, Biochemistry & Behavior, 68, 13-21. Hoffmann, S.E. & Matthews, D.B. (2001). Ethanol-induced impairments in spatial working memory are not due to deficits in learning. Alcoholism: Clinical and Experimental Research, 25, 856-861. Grobin, A.C., Matthews, D.B., Montoya, D., Wilson, W.A., Morrow, A.L., & Swartzwelder, H. S. (2001). Age related differences in neurosteroid potentiation of muscimol-stimulated 36Cl- flux following chronic ethanol treatment. Neuroscience, 105, 547-552. Morrow, A.L., VanDoren M.J., Penland, S.N. & Matthews, D.B. (2001). The Role of GABAergic Neuroactive Steroids in Ethanol Action, Tolerance and Dependence. Brain Research Reviews, 37, 98-109. Matthews, D.B., Morrow, A.L., Tokunaga, S. & McDaniel, J.R. (2002). Acute ethanol administration and acute allopregnanolone administration impair spatial memory in the Morris water task. Alcoholism: Clinical and Experimental Research, 26, 1747-1751. Tokunage, S., McDaniel, J.R., Morrow, A.L. & Matthews, D.B. (2003). Effect of acute ethanol administration and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity. Brain Research, 967, 273-280. Mittleman, G. Van Brunt, C.L. & Matthews D.B. (2003). Schedule induced ethanol self-administration in DBA/2J and C57BL/6J. Alcoholism: Clinical and Experimental Research, 27, 918-925. Silvers, J.M., Tokanaga, S., Mittleman, G. & Matthews D.B. (2003). Chronic intermittent ethanol exposure during adolescence produces metabolic, hypnotic and cognitive tolerance in rats. Alcoholism: Clinical and Experimental Research, 27, 1606-1612. Highlighted article is issue. Morrow, A.L., Khisti, R.T., Tokunaga, S., McDaniel, J.R., Matthews, D.B. (2003). GABAergic Neuroactive steroids modulate selective ethanol actions: Mechanisms and significance. In: Neurosteroid Effects in the Central NervousSystem: The Role of the GABAA Receptor, Smith, S.H. (Ed.) CRC Press LLC, Miami, pp. 219-245 (2003). The Complex Trait Consortium (CTC)* (2003). Lorraine Flaherty, Oduola Abiola, Joe M. Angel, Philip Avner, Alexander A. Bachmanov, John K. Belknap, Beth Bennett, Elizabeth P. Blankenhorn, David A. Blizard, Valerie Bolivar, Gudrun A. Brockmann, Kari J. Buck , Jean-Francois Bureau, William L. Casley, Elissa J. Chesler, James M. Cheverud, Gary A. Churchill, Melloni Cook, John C. Crabbe, Wim E. Crusio Ariel Darvasi, Gerald de Haan Peter Demant, R.W. Doerge, Rosemary W. Elliott, Charles R. Farber, Jonathan Flint, Howard Gershenfeld, John P. Gibson, Weikuan Gu25, Heinz Himmelbauer26, Robert Hitzemann6, Hui-Chen Hsu27, Kent Hunter28, Fuad Iraqi24, Ritsert C. Jansen, Thomas E. Johnson, Byron C. Jones, Gerd Kempermann, Frank Lammert, Lu Lu, Kenneth F. Manly, Douglas B. Matthews, Juan F. Medrano, Margarete Mehrabian, Guy Mittleman, Beverly A. Mock, Jeffrey S. Mogi4, Xavier Montagutelli, Grant Morahan, John D. Mountz , Hiroki Nagase, Richard S. Nowakowski7, Bruce F. O'Hara, Alexander V. Osadchuk, Beverly Paigen, Abraham A. Palmer, Jeremy L Peirce, Daniel Pomp, Michael Rosemann, Glenn D. Rosen, Leonard C. Schalkwyk, Ze'ev Seltzer, Stephen Settle, Kazuhiro Shimomura, Siming Shou, James M. Sikela, Linda D. Siracusa, Jimmy L. Spearow, Cory Teuscher, David W. Threadgill, Linda A. Toth, Ayo A. Toye, Csaba Vadasz, Gary Van Zant Edward, Wakeland, Robert W. Williams, , Huang-Ge Zhang, Fei Zou (2003). The nature and identification of quantitative trait loci: a communitys view. Nature Genetics Reviews, 4, 911-915. Silvers, J. M., Tokunaga, S., Berry, R.B., White, A.M. & Matthews D.B. (2003). Impairments in spatial learning and memory: ethanol, allopregnanolone and the hippocampus. Brain Research Review 967, 273-280. Berry, R.B. & Matthews, D.B. (2004). Acute ethanol administration selectively impairs spatial memory in C57BL/6J Mice. Alcohol, 32, 9-18. Khisti, R.T., VanDoren, M.J., Matthews, D. B. & Morrow A.L. (2004). Ethanol-induced elevation of 3a-hydroxy-5a-pregnan-20-one does not modulate motor in-coordination in rats. Alcoholism: Clinical and Experimental Research, 28, 1249-1256. Matthews, D.B. & Silvers, J.R. (2004). The use of acute ethanol administration as a tool to investigate multiple memory systems. Neurobiology of Learning and Memory. 82, 299-308. Invited Review. The Complex Trait Consortium (2004) Churchill GA, Airey DC, Allayee H, Angel JM, Attie AD, Beatty J, Beavis WD, Belknap JK, Bennett B, Berrettini W, Bleich A, Bogue M, Broman KW, Buck KJ, Buckler E, Burmeister M, Chesler EJ, Cheverud JM, Clapcote S, Cook MN, Cox RD, Crabbe JC, Crusio WE, Darvasi A, Deschepper CF, Doerge RW, Farber CR, Forejt J, Gaile D, Garlow SJ, Geiger H, Gershenfeld H, Gordon T, Gu J, Gu W, de Haan G, Hayes NL, Heller C, Himmelbauer H, Hitzemann R, Hunter K, Hsu HC, Iraqi FA, Ivandic B, Jacob HJ, Jansen RC, Jepsen KJ, Johnson DK, Johnson TE, Kempermann G, Kendziorski C, Kotb M, Kooy RF, Llamas B, Lammert F, Lassalle JM, Lowenstein PR, Lu L, Lusis A, Manly KF, Marcucio R, Matthews D, Medrano JF, Miller DR, Mittleman G, Mock BA, Mogil JS, Montagutelli X, Morahan G, Morris DG, Mott R, Nadeau JH, Nagase H, Nowakowski RS, O'hara BF, Osadchuk AV, Page GP, Paigen B, Paigen K, Palmer AA, Pan HJ, Peltonen-Palotie L, Peirce J, Pomp D, Pravenec M, Prows DR, Qi Z, Reeves RH, Roder J, Rosen GD, Schadt EE, Schalkwyk LC, Seltzer Z, Shimomura K, Shou S, Sillanpaa MJ, Siracusa LD, Snoeck HW, Spearow JL, Svenson K, Tarantino LM, Threadgill D, Toth LA, Valdar W, de Villena FP, Warden C, Whatley S, Williams RW, Wiltshire T, Yi N, Zhang D, Zhang M, Zou F. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics, 36, 1133-1137. Matthews, D.B. (2004). Neuroactive steroids and ethanol-induced decreases in spatial cognitive processing. Proceedings of the 31st International Medical Advisory Group Conference, 31, 85-90. Kralic, J.E., Criswell, H.E., Osterman, J., OBuckley, T.K., Matthews, D.B., Hamre, K., Breese, G.R., Homanics, G.E. & Morrow, A.L. (2005). Genetic essential tremor in GABAA (1 subunit knockout mice. Journal of Clinical Investigation, 115: 774-779. Matthews, D.B., Bhave, S.V., Belknap, J.K., Brittingham, C., Chesler, E.J., Hitzemann, R.J., Hoffmann, P.L., Lu, L., McWeeney, S., Miles, M.F., Tabakoff, B. & Williams, R.W. (2005). Complex genetics of interactions of alcohol and CNS function and behavior. Alcoholism: Clinical and Experimental Research, 29: 1706-1719. Tokunaga, S., Silvers, J. & Matthews, D.B. (2006). Chronic intermittent ethanol exposure during adolescence blocks ethanol-induced inhibition of spontaneously active hippocampal pyramidal neurons. Alcoholism: Clinical and Experimental Research, 30, 1-6. Goldowitz, D., Matthews, D.B., Hamre, K.M., Mittleman, G., Chesler, E.J., Becker H. C., Lopez, M.F., Jones, S.R., Mathews, T.A., Miles, M.F., Kerns, R. & Grant, K.A. (2006). Progress in using mouse inbred strains, consomics and mutants to identify genes related to stress, anxiety and alcohol phenotypes. Alcoholism: Clinical and Experimental Research, 30, 1066-1078. Werner, D.F., Blednov, Y.A., Ariwodola, O.J., Silberman, Y., Logan, E., Berry, R.B., Borghese, C., Matthews, D.B., Weiner, J.L., Harrison, N.L., Harris, R.A., Homanics, G.E. (2006). Knock-in mice with ethanol-insensitive alpha1-containing GABAA receptors display selective alterations in behavioral responses to ethanol, Journal of Pharmacology and Experimental Therapeutics, 319, 219-227. Silvers, J.M., Tokunaga, S., Mittleman, G., OBuckley, T., Morrow, A.L. & Matthews, D.B. (2006). Chronic intermittent ethanol exposure during adolescence reduces the effect of ethanol challenge on hippocampal allopregnanolone levels and Morris water maze task performance, Alcohol, 151-158. Hamre, K.M, Wilkenson, S., Goldowitz, D.G. & Matthews, D.B. (2007). Screening for ENU-Induced mutations in mice that result in aberrant ethanol-related phenotype. Behavioral Neuroscience, 121, 665-678. Goa, J., Maison, S.F., Wu, X., Hirose, K., Jones, S.M., Bayazitov, I., Tian, Y., Mittleman, G., Matthews D.B., Zakharenko, S., Liberman, M.C. & Zuo, J. (2007). The orphan glutamate receptor [d]1 subunit is required for high-frequency hearing. Molecular Cellular Biology, 27, 4500-4512. Matthews, D.B., Morrow, A.L., OBuckley, T., Berry, R.B., Mittleman, G., Goldowitz, D., Tokunaga, S. & Silvers, J.M. (2008). The effect of acute mild footshock on ethanol self-administration and plasma corticosterone levels in three commonly used mouse strains. Alcohol, 42, 469-476. Matthews, D.B., Chesler, E.J., Cook, M.N, Cockroft, J., Philip, V.M. & Goldowitz, D (2008). Genetic mapping of vocalization to a series of increasing acute footshocks using B6.A consomic and B6.D2 congenic mouse strains. Behavior Genetics, 38, 417-423. Awarded Fulker Award from Behavior Genetics Association. Berry, R.B., Werner, D.E., Wang, X., Mittleman, G., Jablonski M.M., Homanics, G.E. & Matthews, D.B. (2008). Mice with Targeted Genetic Reduction of GABAA Receptor a1 Subunits Display Performance Differences in Morris Water Maze Tasks. Neurobiology of Learning and Memory, 90, 580-583. Matthews, D.B., Tinsley, K., Diaz-Granados, J.L., Tokunaga, S. and Silvers, J.M. (2008). Chronic intermittent exposure to ethanol during adolescence produces tolerance to the hypnotic effects of ethanol in male rats: a dose dependent analysis. Alcohol, 42, 617-621. Berry, R.B., Chandra, D., Diaz-Granados, J.E., Homanics, G.E. & Matthews, D.B. (2009). Investigation of ethanol-induced impairment of spatial memory in 2 heterozygous knockout mice. Neuroscience Letters, 455, 84-87. Kumar, S., Porcu, P., Werner, D.F., Matthews, D.B., Diaz-Granados, J.L., Helfand, R.S., & Morrow, A.L. (2009). The Role of GABAA Receptors in the Acute and Chronic Effects of Ethanol: A Decade of Progress. Psychopharmacology, 205, 529-564. Matthews, D.B. (2010). Adolescence and Alcohol: Recent Advances in Understanding the Impact of Alcohol Use During A Critical Developmental Window. Alcohol, 44, 1-2. Chin, V.S., Van Skike, C.E. & Matthews, D.B. (2010). Effects of Ethanol on Hippocampal Function during Adolescence: A Look at the Past and Thoughts on the Future. Alcohol, 44, 3-14. Philip, V.M, Duvurru, S, Gomero, B, Ansah, T.A., Blaha, C.D., Cook, M.N., Hamre, K.M., Lariviere, R.W., Matthews, D.B., Mittleman, G., Goldowitz, D., & Chesler, E.J. (2010). High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes, Brain and Behavior, 9, 129-159. Van Skike, C.E., Botta, P., Chin, V.S., Tokunaga, S., McDaniel, J.M., Venard, J., Diaz-Granados, J.L., Valenzuela, C.F. & Matthews, D.B. (2010). Behavioral Effects of Ethanol in Cerebellum are Age Dependent: Potential System and Molecular Mechanisms. Alcoholism: Clinical and Experimental Research, 34, 2070-2080. Mittleman, G., Call, S.B., Cockroft, J.L, Goldowitz, D., Matthews, D.B., & Blaha, C.D. (2011). Dopamine dynamics associated with, and resulting from, schedule-induced alcohol Self-administration: Analyses in dopamine transporter knockout mice. Alcohol, 45, 325-339. Chin, V.S., Van Skike, C.E., Berry, R.B., Kirk, R.E., Diaz-Granados, J., & Matthews, D.B. (2011). Effect of acute ethanol and acute allopregnanolone on spatial memory in adolescent and adult rats. Alcohol, 45, 473-483. Du, X., Elberger, A.J., Matthews, D.B. & Hamre, K.M. (2012). Heterozygous deletion of NR1 subunit of the NMDA receptor alters ethanol-related behaviors and regional expression of NR2 subunits in the brain. Neurotoxicology and Teratology, 34, 177-186. Novier, A, Van Skike, C.E., Chin, V.S., Diaz-Granados, J.L., & Matthews, D.B. (2012). Effects of Low Dose Acute Ethanol on Cognition and Movement in Adolescent and Adult Rats. Neuroscience Letters, 512, 38-42. Van Skike, C.E., Novier, A.K., Diaz-Granados, J.L. & Matthews, D.B. (2012). Adolescent spatial memory is resilient to chronic intermittent ethanol exposure: The dissociation of metabolic and cognitive tolerance. Brain Research, 1453, 34-39. Novier, A., Van Skike, C.E., Diaz-Granados, JL., Mittleman, G., & Matthews, DB. (2013). Acute Alcohol Produces Ataxia and Cognitive Impairments in Aged Animals: A Comparison Between Young Adults and Aged Rats. Alcoholism: Clinical and Experimental Research, 37, 1317-1324. Zandy, S.L., Pang, J.S., Ho, M.H. & Matthews, D.B. (2013). Singaporean college students overpour drinks similar to Western populations: Influence of peer presence in a simulated alcohol-pouring task. Alcoholism: Clinical and Experimental Research, 37, 1963-1970. Squeglia, L. M., Boissoneault, J., Van Skike, C. E., Nixon, S. J., & Matthews, D. B. (2014). Differential effects of alcohol across the lifespan: Recent insights from adolescent, adult, and aged populations using human and animal models. Alcoholism: Clinical and Experimental Research, 38, 2509-2516. Zandy, S.L*., Matthews, D.B.*, Tokunaga, S., Miller, A., Blaha, C.D. & Mittleman, G. (2015). Reduced dopamine release in the nucleus accumbens core of adult rats following adolescent alcohol exposure: age and dose-dependent analysis. Psychopharmacology, 232, 777-784. *denotes equal contribution. Van Skike, C.E., Diaz-Granados, J.L. & Matthews, D.B. (2015). Chronic intermittent ethanol exposure produces persistent anxiety in adolescent and adult rats. Alcoholism, Clinical and Experimental Research, 39, 262-271. Ornelas, L.C., Novier, A., Van Skike, C.E., Diaz-Granados, J.L & Matthews, D.B. (2015). The effects of acute ethanol on motor impairments in adolescent, adult and aged rats. Alcohol, 49, 121-126. Novier, A., Diaz-Granados, J.L. & Matthews, D.B. (2015). Alcohol use across the lifespan: An analysis of adolescent and aged rodents and humans. Pharmacology, Biochemistry and Behavior, 133, 65-82. Van Skike, C.E., Zandy, S.L. & Matthews, D.B. (2016). Substance use in adolescence. In Puberty: Physiology and Abnormalities, Eds, Philip Kumanov and Ashok Agarwal, pp 273-285. Novier, A., Ornelas, L.C., Diaz-Granados, J.L. & Matthews, D.B. (2016). Differences in Behavioral Responding in Adult and Aged rats following Chronic Ethanol Exposure. Alcoholism: Clinical and Experimental Research, 40, 1462-1472. Matthews, D.B., Novier, A., Diaz-Granados, J.L., Van Skike, C.E., Ornelas, L. & Mittleman, G. (2017). Impact of adolescent alcohol use across the lifespan: Long-lasting tolerance to high dose alcohol coupled with potentiated spatial memory impairments to moderate dose alcohol. Alcohol, 61, 33-42. Matthews, D.B. & Mittleman, G. (2017). Age-dependent effects of chronic intermittent ethanol treatment: Gross motor behavior and body weight in aged, adult and adolescent rats. Neuroscience Letters, 657, 146-150. Matthews, D.B., Watson, M.R., James, K., Kastner, A., Schneider, A., & Mittleman, G. (2019). The impact of low to moderate chronic intermittent alcohol exposure on behavioral endpoints in aged, adult and adolescent rats. Alcohol, 78, 33-42. Van Skike, C.E., Goodlett, C. & Matthews, D.B. (2019). Acute alcohol and cognition: Remembering what it causes us to forget. Alcohol, 79, 105-125. Invited review. Matthews, D.B., Schneider, A., Kastner,, A., Scaletty, S. & Szenay, R. (2019). I cant drink what I used to: The interaction between ethanol and the aging brain. International Review of Neurobiology, 148, 79-99. Watson, M.R., James, K., Mittleman, G. & Matthews, D.B. (2020). Impact of acute ethanol exposure on body temperatures in aged, adult and adolescent male rats. Alcohol, 82, 81-89. Matthews, D.B., Scaletty, S., Schreiber, A. & Trapp, S. (2020). Acute ethanol administration produces larger spatial and nonspatial memory impairments in 29-33 month old rats compared to adult and 18-24 month old rats. Pharmacology, Biochemistry and Behavior, 199, 173074,  HYPERLINK "https://doi.org/10.1016/j.pbb.2020.173074" \o "Persistent link using digital object identifier" \t "_blank" https://doi.org/10.1016/j.pbb.2020.173074 Van Skike, C.E. & Matthews, D.B. (2021). Alcohol and the Aging Brain: Increased alcohol sensitivity potentially magnifying oxidative stress. In The Neuroscience of Aging, pp 225-232 in Assessments, Treatments and Modeling in Aging and Neurological Disease, Editors: Martin, Preedy & Rajendram. Bauer, M.R., Hasenberg, W., Bakalars, Mittleman, G. & Matthews D.B. (2021). Reinstating over-pouring behavior: Importance of the imagined drinking context. Substance Use and Misuse, 56, 1374-1382, doi: 10.1080/10826084.2021.1928209. Matthews, D.B. & Imhoff, B.M. (2022). Age modifies the effect of ethanol on behavior: Investigations in adolescent, adult and aged rats. International Review of Neurobiology, 161, 251-275, doi:  HYPERLINK "https://doi.org/10.1016/bs.irn.2021.06.010" \o "Persistent link using digital object identifier" \t "_blank" https://doi.org/10.1016/bs.irn.2021.06.010 Matthews, D.B., Scaletty, S., Trapp, S., Kastner, A., Schneider, A., Schreiber, A & Rossmann, G. (2022). Chronic intermittent ethanol administration during adolescence produces sex dependent impairments in behavioral flexibility and survivability. Brain Sciences, 12, 606,  HYPERLINK "https://doi.org/10.3390/brainsci12050606" https://doi.org/10.3390/brainsci12050606. Ho AM, Peyton MP, Scaletty SJ, Trapp S, Schreiber A, Madden BJ, Choi DS, Matthews DB (2022). Chronic Intermittent Ethanol Exposure Alters Behavioral Flexibility in Aged Rats Compared to Adult Rats and Modifies Protein and Protein Pathways Related to Alzheimer's Disease. ACS Omega. Dec 7;7(50):46260-46276. doi: 10.1021/acsomega.2c04528. PMID: 36570296; PMCID: PMC9774340. Matthews, D.B. & Rossmann, G. (2023). Using animal models to identify clinical risk factors in the older population due to alcohol use and misuse. Alcohol, 107, 38-43. Matthews, D.B., Keyes, Katherine & Ramchandani, V.A. (2023). Alcohol and Aging. Alcohol, 107, 1. Matthews, D.B. & Koob, G.F. (2023). On the critical need to investigate the effect of alcohol in the older population. Alcohol, 107, 2-3. Sharma, P., Matthews, D.B., Nguyen, Q.A., Rossmann, G.L., Patten, C. & Hammond, C.J. (2023). Old dog, new tricks: Identifying and addressing youth cannabis vaping in the clinical setting. Clinical Medicine Insights: Pediatrics, 17, 1-6. Mwendwa-Karinge, C., Muehlenkamp, J.J., Matthews, D.B. & Wilfridah, M. (2023). The role of trait impulsivity on suicidal behaviors in the emerging adult in Kenya. Emerging Adulthood 11, 884-892. HYPERLINK "https://doi.org/10.1177/21676968231168923"https://doi.org/10.1177/21676968231168923 Sharma, P., Nguyen, Q.A., Matthews, S.J., Carpenter, E., Matthews, D.B., Patten, C.A., Hammond, C.J. (2023). Psilocybin history, action and reaction: A narrative clinical review. Journal of Psychopharmacology, 1-17, HYPERLINK "https://doi.org/10.1177/02698811231190858"https://doi.org/10.1177/02698811231190858. Matthews, D.B., Scaletty, S., Trapp, S., Schreiber, A., Rossmann, G., Imhoff, B., Petersilka, Q, Kastner, A., Pauly, J. & Nixon, K. (2023). Chronic intermittent ethanol exposure during adolescence produces sex- and age-dependent changes in anxiety and cognition without changes in microglia reactivity late in life. Frontiers in Behavioral Neuroscience, 17, doi: 10.3389/fnbeh.2023.1223883 Matthews, D.B. (2024). Who you follow is important. Alcohol, 114, 41-42. Matthews, D.B., Rossmann, G., Matthews, S.J., Zank, A., Shult, C., Turunen,A. & Sharma, P. (2024). Increased anxiolytic effect in aged female rats and increased motoric behavior in aged male rats to acute alcohol administration: Comparison to younger animals. Pharmacology, Biochemistry & Behavior, 239, 173770. Matthews, D.B., Kerr, E., Zank, A, Hartwig, J., Garscia, A., Stumo, S. & Sharma, P. (in press). Recent investigations designed to unravel the interaction of aging and alcohol on behavior, cognition and potential neurobiological mechanisms. In Effects of Alcohol on the Brain across the lifespan Recent Advances from Preclinical Studies. Edited by Fernando Vaalenzuela, David L Linsenbardt and Jeffrey L. Weiner. Matthews, D.B. & Kerr, E. (submitted). Interaction of age and sex as factors in understanding the anxiolytic effects of alcohol: Unasked questions limiting the understanding of a critical health issue. Pharmacology, Biochemistry & Behavior. Hartwig, J., Kendrick, J., Ahmad, G., Cook, J., Matthews, D.B. & Sharma, P. (submitted). Exploring User Experiences with Amanita Muscaria: A thematic analysis of Reddit online forum discussions. Toxicology Research. Undergraduate students with first position following graduation Charles Bakalars, 2016 Northern Colorado University, Masters in Counseling Whitney Hasenberg, 2018 University of Wisconsin Stout, Masters in School Counseling Meredith Watson, 2018 Indiana University Purdue University Indianapolis, PhD Behavioral Neuroscience Kimberly James, 2018 University of Buffalo, PhD Behavioral Neuroscience Amelia Schneider, 2020 University of Minnesota, PhD Neuroscience Abigail Kastner, 2020 Medical University of South Carolina, PhD Neuroscience Katie George, 2021 University of Minnesota, PhD School Psychology Sarah Trapp, 2021 Binghamton University, PhD Behavioral Neuroscience Samantha Scaletty, 2021 Mayo Healthcare Graduate School, PhD Medical Pharmacology Areonna Schreiber, 2022 Mayo Healthcare Graduate School, PhD, Biomedical Engineering Victoria Tilloston, 2022 Auburn University, Masters in Counseling Tia Weiden, 2022 Wake Forest University, Masters in Clinical Research Management Bailey Imhoff, 2023 University of Southern Mississippi, PhD, School Psychology Carolyn Shult, 2024 University of Wisconsin Madison, PhD, Nutrition & Metabolism Emily Kerr, 2024 Binghamton University, PhD Behavioral Neuroscience Ava Brey, 2024 Medical College of Wisconsin, M.D. student Undergraduate students with paid summer research internships Meredith Watson, University of Missouri Abigail Kastner, Marquette University Amelia Schneider, Medical University of South Carolina Abigail Kastner, Medical University of South Carolina Samantha Scaletty, University of Illinois, Urbana-Champaign Samantha Scaletty, Mayo Healthcare Rochester MN Tia Wieden, Mayo Healthcare Rochester MN Carolyn Shult, Medical College of Wisconsin, Milwaukee WI Alicia Turenun, Medical University of South Carolina Carolyn Shult, Medical College of Wisconsin, Milwaukee WI Ph D GRADUATES with first position following degree Adelle Novier, 2015 Researcher Private Industry Candice Van Skike, 2013 Post-Doctoral Researcher University of Kentucky Department of Pharmacy Ray Berry, 2009 Post-Doctoral researcher Dept of Developmental Neurobiology St. Judes Childrens Research Hospital, Memphis TN Janelle Silvers, 2005 Post-Doctoral research Department of Psychology University of South Carolina Sayaka Tokunaga, 2005 Dept of Anatomy University of Tennessee Health Science Center GRADUATE COMMITTEE Masters Committee Doctoral Committee Sarah Hoffman (Chair), 2001 Mary Houts, 2000 Sayaka Tokunaga (Chair), 2002 Bonnie Nagel, 2002 Janelle Silvers (Chair), 2002 Sayaka Tokunaga (Chair), 2005 Andrea Booth, 2006 Janelle Silvers (Chair), 2005 Ray Berry (Chair), 2004 Carrie Van Brunt (2002) Kristy Tinsley (Chair), 2006 Melissa Duncan-Fallon (2002) Vivien Chin (Chair), 2011 Ray Berry (Chair), 2009 Candice Van Skike, 2011 Candice Van Skike (Chair), 2013 Adelle Novier, 2012 Adelle Novier (Chair), 2015 Paige Marsland (Committee), 2023 UNDERGRADUATE COMMITTEE Brad Pounders, University College, Chair, 2001. Jana Skeen, University College, Chair, 2003. Lindsey Rice, Psychology Honors Program, reader, 2006. Melanie Arndt, Biology Honors Program, Baylor University, Chair, 2009. PRESENTATIONS Renner, M.J., Matthews, D.B. & Pierre, P.J. Factors influencing object investigation in rats: a cumulative analysis. Presentation at the Psychonomic Society, November 1992. Best, P.J. & Matthews, D.B. Acute ethanol alters hippocampal place cells. Presentation at the 6th annual Midwestern Hippocampal Conference, June 1994. Best, P.J., Simson, P.E. & Matthews, D.B. Acute ethanol alters hippocampal place cells. Presentation at the Effects of Acute Ethanol on Brain Limbic Mechanisms, Symposium at the annual Research Society on Alcoholism, June 1995. Matthews, D.B. & Dietz-Uhler, B. The effects of political advertisements on political-group identity. Presentation at the Current Applications of Social Identity Theory symposium, Eastern Psychological Association, March 1996. Best, P.J., Matthews, D.B. & Simson, P.E. Brain mechanisms of alcohol induced spatial cognitive deficits. Invited paper. Midwestern Psychological Association, May 1996. Matthews, D.B. Spatial learning and septal electrophysiology. Fetal Alcohol Research Group, June 1996. Matthews, D.B. Effect of ethanol on spatial cognitive processing. Presentation at the Ethanol and the hippocampal system: Behavior to molecular biology symposium at the annual American Psychological Society meeting, May 1998. (Symposia organizer). Matthews, D.B. Neurosteriods contribute to electrophysiological effects of ethanol in the medial septal nucleus. Presentation at the Neurosteriods mediate pharmacological effects of ethanol: A new mechanism of ethanol action? symposium at the annual Research Society on Alcoholism, June 1999. Matthews, D.B., Van Doren, M.J. & Morrow, A.L. Ethanol inhibition of medial septal/diagonal band of Broca spontaneous neural activity is modulated by allopregnanolone. Ethanol and Cell Signaling symposium, American Society for Biochemistry and Molecular Biology, October 1999. Matthews, D.B., Ethanol impairs cognitive processing. Symposium at the annual Research Society on Alcoholism, June, 2000. (Symposia organizer and chair). Matthews, D.B. Neurosteroids mimic and may contribute to effects of ethanol on cognitive performance in rats. Ethanol Sensitivity of GABAA Receptors In Vitro and In Vivo, Research Society on Alcoholism Poster Discussion, June, 2001. Matthews, D.B. Development of a high throughput ethanol screen to test mice with single base pair mutations. Presentation at the Use of Genetic and Neurobiological Screens for Understanding the Basis of Alcoholism symposium at the annual Research Society on Alcoholism, June, 2001. Matthews, D.B. Impairments in spatial cognitive processing: Ethanol, allopregnanolone and the hippocampus. Symposium at the European Behavioural Pharmacology Society and European Brain and Behaviour Society, September, 2001 Matthews D.B., Tokunaga, S., Silvers, J.M. & Morrow A.L. Steroid neurogenesis is critical for ethanol induced cognitive impairments to moderate ethanol doses. Symposium at the International Behavioral Neuroscience Meeting, April 2003. Matthews, D.B. Steroidogenesis is critical for spatial memory impairments produced by moderate doses of ethanol. Research Society on Alcoholism, 2003. Plenary Lecture. Matthews, D.B. Neuroactive steroids and ethanol-induced decreases in spatial cognitive processing. 31st International Medical Advisory Group, October, 2003. Matthews, D.B., Lu, L., Chesler, E.J. & Williams, R.W. (2004). Use of WEBqtl to identify QTLs associated with footshock stress and ethanol related behaviors. Symposium at the Research Society on Alcoholism, June, 2004. (Symposia co-organizer). Matthews, D.B., Chesler, E., Williams, R.W., Hamre K & Goldowitz G. (2005). High-throughput screening for ethanol phenotypes. Symposium at the Research Society on Alcoholism, June, 2005. Morrow, A.L., Penland, P.N., Khisti, R.T., Porcu, P. & Matthews, D.B. (2005). GABAergic neuroactive steroids contribute to ethanol action in the CNS. Symposium at the Research Society on Alcoholism, June, 2005. Matthews, D.B., Silvers, J.M., Tokunaga, S. & Morrow, A.L. (2005). Binge alcohol exposure during adolescence produces behavioral, electrophysiological and biochemical adaptations in hippocampus. Symposium and platform presentation at the Neurobehavioral Teratology Society, June, 2005. Matthews, D.B. (2006). Binge alcohol exposure during adolescence produces behavioral, electrophysiological and biochemical adaptations in hippocampus. Symposium at the Research Society on alcoholism, June, 2006. (Symposia organizer and chair). Matthews, D.B., Van Skike, C.E., Botta, P., Chin, V.S., Silvers, J.M., Diaz-Granados, J.L. & Valenzuela, C.F. (2010). Behavioral effects of ethanol in cerebellum are age-dependent: Potential system and molecular mechanisms. Symposium at the Research Society on Alcoholism, June, 2010. (Symposia organizer and chair) Matthews, D.B. (2011). Potential neurochemical and neurophysiological mechanisms underlying adolescence insensitivity to ethanols ataxic effects. Society for Neurochemistry, India. Plenary Lecture Van Skike, C.E., Diaz-Granados, J.L. & Matthews, D.B. (2013). Behavioral, electrophysiological, and molecular differences between adolescent and adult rats in response to ethanol. Symposium presented at the Research Society on Alcoholism, Orlando, Fl. Matthews, D.B. (2013). Aged rats are more impaired to acute ethanol than adult rats. Symposium presented at the Research Society on Alcoholism, Orlando, Fl. (Symposia organizer and chair) Matthews, D.B. (2016). Impact of acute or chronic alcohol exposure in aged rodents. Part of Aging and Alcohol symposium at the Research Society on Alcoholism, New Orleans, LA. Matthews, D.B. (2016). The Dangerous Interaction of Age and Alcohol. International Conference on Gerentology, Tiaan China. Matthews, D.B., Watson, M; James, K; Kastner, A; Schneider, A. (2018). Alcohol and Cognition: Impact Across the Lifespan. Part of Neuroscience of Addiction: Animal Models and Human Risk Factors symposium at Midwestern Psychological Association, Chicago, IL. Matthews, D.B. (2019). Understanding the impact of ethanol in aged animals. Symposium presentation presented at the Research Society of Alcoholism, Minneapolis, MN (Symposia organizer and chair). Matthews, D.B. (2019). Understanding the interaction of ethanol and the aging brain. Plenary Lecture at the International Summit on Brain Sciences, Xian China. Matthews, D.B. (2020). Increased sensitivity to ethanol in aged animals: Implications for ethanol drinking and ethanol addiction. Symposium presentation at the Latin American Society for Biomedical Research on Alcoholism, Sao Paulo, Brazil (virtual). Matthews, D.B. (2021). Increased sensitivity to ethanol in aged animals: potential neurobiological mechanisms. Symposium presented at the European Society for the Biomedical Study of Alcoholism. Romania. Matthews, D.B. (2021). But Its the Wisconsin Tradition: Age as a Factor in Understanding Alcohol Use and Misuse. Academic Grand Rounds. Northwest Wisconsin Mayo Healthcare. Matthews, D.B. (2022). Using animal models to identify clinical risk factors in the older population due to alcohol use and misuse. Wisconsin Alzheimers Institute, Core Skills Training. Matthews, D.B. (2022). Alcohol and Aging. Wisconsin Neurological Society. Matthews, D.B. (2022). Roundtable discussion on alcohol use disorders in special populations and the role of psychology and ACTs teams. Presentation on Alcohol and the Aged Population. British Society of Gastroenterology annual meeting. Matthews, D.B., Rossmann, G., Wieden, T., Shult, C., Turunen, A., Matthews, S.J., Petersilka, Q & Oliver, P. (2023). Identification of potential mechanisms impacting the effect of alcohol in aged rats. Symposium presented at the annual Research Society on Alcohol conference. (Symposium organizer). Matthews, D.B. (2023). Chronic Intermittent Ethanol Alters Cognition and Hippocampal Protein Pathways Associated with Alzheimers Disease: Insights from Adolescent- and Aged-Exposed Animals. Joint National Institute on Aging and National Institute on Alcohol Abuse and Alcoholism workshop titled Role of Alcohol Misuse in the Onset and Progression of Alzheimers Disease and Its Related Dementias. SELECTED POSTERS Matthews, D.B. & Best, P.J. (1993). Fimbria/fornix lesions affect place learning but not response learning in the rat. Neuroscience Abstracts, 19, 529. Matthews, D.B., Vandergriff, J.L., Kendrick, W.T., Simson, P.E. & Best, P.J. (1994). Ethanol impairs a previously learned spatial response in the rats: comparisons with diazepam and MK-801. Alcoholism: Clinical and Experimental Research, 18, 520. Matthews, D.B., Simson, P.E. & Best, P.J. (1994). Ethanol disrupts activity of hippocampal place cells in awake behaving rats. Alcoholism: Clinical and Experimental Research, 18, 520. Kedrick, W.T., Vandergriff, J.L, Matthews, D.B., Best, P.J. & Simson, P.E. (1994). Ethanol impairs place learning but not response learning in the rat. Neuroscience Abstracts, 20, 1764. Matthews, D.B., Simson, P.E. & Best, P.J. (1995). Acute ethanol impairs the use of spatial memory under a variety of task demands. Alcoholism: Clinical and Experimental Research, 19, 64A. White, A.M., Matthews, D.B. & Best, P.J. (1995). Fimbria/fornix lesions enhance performance on a non-spatial trajectory task in the water maze. Neuroscience Abstracts, 21, 1942. Matthews, D.B., White, A.M., Brush, E.D. & Best, P.J. (1995). Construction of the spatial cognitive map does not require active exploration of the environment. Neuroscience Abstracts, 21, 2086. Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Acute administration of ethanol impairs spatial memory. Alcoholism: Clinical and Experimental Research, 20, 64A. Dror, I.E., Hays, A., Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Risk taking under the influence of ethanol. Alcoholism: Clinical and Experimental Research, 20, 111A. Matthews, D.B., Simson, P.E. & Best, P.J. (1996). Spatial memory deficits in adult rats exposed to ethanol during gestation. Alcoholism: Clinical and Experimental Research, 20, 73A. Matthews, D.B. & Best, P.J. (1996). Effect of intra- and extra-maze cues on place field location. Neuroscience Abstracts 22, 914. Matthews, D.B, Maier, S.E., Miller, J.A., West, J.R., Best, P.J. & Simson, P.E. (1997). Prenatal exposure to ethanol differentially alters the effect of an ethanol challenge on spatial cognitive processing in the rat. Alcoholism: Clinical and Experimental Research, 21, 117A. Matthews, D.B., Groark, B., Best, P.J. & Simson, P.E. (1997). Opposite effects of two levels of prenatal exposure to ethanol on responses of medial septal neurons to an ethanol challenge. Alcoholism: Clinical and Experimental Research, 21, 83A. Matthews, D.B., Fritschy, J.M., Sieghart, W., Devaud, L.L., and Morrow, A.L. (1997). Differential effects of 2-week and 6-week chronic ethanol consumption on GABAA receptor peptide expression in rat hippocampus. Neuroscience Abstracts, 23, 2402. Grobin, A.C., Matthews, D.B., Sieghart, W., Devaud, L.L. & Morrow, A.L. (1998). Regional variations in changes in GABAA receptor subunit peptide in the cortex of ethanol dependent rats. Alcoholism: Clinical and Experimental Research, 22, 10A. Matthews, D.B., Criswell, H.E., Devaud, L.L., Breese, G.R. & Morrow, A.L. (1998). Chronic ethanol consumption alters the recovery of spontaneous medial septal activity from GABA microiontophoresis in rats. Alcoholism: Clinical and Experimental Research, 22, 10A. Matthews, D.B., Devaud, L.L., Kralic, J.E., Fritschy, J.M., Sieghart, W. & Morrow, A.L. (1998). Chronic MK-801 administration alters GABA A receptor subunit peptide expression and function in the rat. Neuroscience Abstracts, 24, 1831. Van Doren, M.J., Matthews, D.B., Janis, G.C., Grobin, A.C., Devaud, L.L. & Morrow, A.L. (1999). Neuroactive steroids modulate ethanol effects in brain. Alcoholism: Clinical and Experimental Research, 23, 14A Matthews, DB., Van Doren, M.J. & Morrow, A.L. (1999). Finasteride pretreatment prevents ethanol-induced inhibition of spontaneous neural activity in medial septal/diagonal band of Broca (MS/DB) neurons. Alcoholism: Clinical and Experimental Research, 23, 15A Kralic, J.E., Matthews, D.B., Kampov-Polevoi, A.B., Overstreet, D.H., Gause, L.R., McCown, T., & Morrow, A.L. (1999). Development of ethanol dependence after self-administration in alcohol preferring P rats. Neuroscience Abstracts, 25, 1078. Montoya, D., Grobin, A.C., Morrow, A.L., Matthews, D.B., Wilson, W.A. & Swartzwelder, H.S. (1999). Differential effects of ethanol on muscimol-stimulated 36Cl- Uptake in adolescent vs. adult cortex. Neuroscience Abstracts, 25, 1577. Morrow, A.L., Janis, G.C., VanDoren, M.J., Matthews, D.B., Grobin, A.C. & Devaud, L.L. (1999). Ethanol elevates plasma and brain levels of the neurosteriod 3(-hydroxy-5(-pregnan-20-one: A novel mechanism of ethanol action. Neuroscience Abstracts, 25, 1808. VanDoren, M.J., Matthews, D.B. & Morrow, A.L. (1999). The neurosteriod 3(-hydroxy-5(-pregnan-20-one contributes to behavioral effects of ethanol. Neuroscience Abstracts, 25, 1808. Matthews, D.B., VanDoren, M.J. & Morrow, A.L. (1999). Finasteride pretreatment selectively blocks ethanol-induced inhibition of spontaneous medial septal/diagonal band of Broca neurons. Neuroscience Abstracts, 25, 1808. VanDoren, M.J., Matthews, D.B., Overstreet, D.H., & Morrow, A.L. (2000). GABAergic neurosteriod 3(-hydroxy-5(-pregnan-20-one modulates alcohol intake in P rats. Alcoholism: Clinical and Experimental Research, 24, 15A. Hoffman, S.E. & Matthews, D.B. (2000) Acute ethanol administration selectively impairs spatial working memory in a temporary and dose-dependent manner. Alcoholism: Clinical and Experimental Research, 24, 87A. Hoffmann, S.E., Best, P.J. & Matthews, D.B. (2000) Spatial vs. non-spatial and working vs. reference memory theories of hippocampal function: Acute ethanol administration as an investigative tool. Society for Neuroscience Abstracts McDaniel, J.R., Tokunaga, S. & Matthews, D.B. (2001). Chronic intermittent ethanol exposure produces profound tolerance in adolescent rats. Alcoholism: Clinical and Experimental Research, 25, 13A. Tokunaga, S., McDaniel J.R., Morrow, A.L. & Matthews, D.B. (2001). Comparison of acute ethanol and acute allopregnanolone administration on hippocampal neurophysiology and function. Alcoholism: Clinical and Experimental Research, 25, 14A. Matthews, D.B., Morrow, A.L., Tokanaga, S. & MacDaniel, J.R. (2001). Impairments in spatial cognitive processing: Ethanol, allopregnanolone and the hippocampus. Behavioural Pharmacology, 12, S63. Mittleman, G., Van Brunt, C.L. & Matthews, D.B. (2002). Adjunctive ethanol self-admininstration in DBA/2J and C57BL/6J Mice. Alcoholism: Clinical and Experimental Research, 26, 61A. Hamre, K.M., Matthews D.B., Wilkinson, S., Mittleman, G., Rinchik, G. & Goldowitz, D. (2002). Screening for aberrant alcohol-induced phenotypes and alcohol consumption in ENU-mutagenized mice using a regional mutagenesis approach. Alcoholism: Clinical and Experimental Research 26, 97A. Tokunaga, S., McDaniel, J.R., Morrow, A.L. & Matthews D.B. (2002). Acute ethanol and acute allopregnanolone administration produces similar effects on spontaneous hippocampal pyramidal cell neural activity in anesthetized rats. Alcoholism: Clinical and Experimental Research, 26, 104A. Berry, R.B. & Matthews, D.B. (2002). Acute ethanol administration selectively impairs spatial memory in C57BL/6J mice. Alcoholism: Clinical and Experimental Research, 26, 153A. McDaniel, J.R., Tokunaga, S., Morrow, A.L. & Matthews, D.B. (2002). Chronic intermittent ethanol exposure in adolescent rats produces tolerance to ethanol-induced spatial memory deficits and ethanol-induced allopregnanolone increases. Alcoholism: Clinical and Experimental Research, 26, 153A. Matthews, D.B., Hamre, K.M., Mittleman, G., Wilkinson, S., Rinchik, G. and Goldowitz, D. (2002). High-throughput screen to identify aberrant phenotypes to ethanol or cocaine exposure from ENU-mutagenized mice. Behavioural Pharmacology, 13, 493. Goldowitz, D., Matthews D.B. & Hamre, K.M. (2003). Use of consomic strains as a systematic, whole genome, high throughput first past screen for the localization of genes relative to alcohol-related phenotypes. Alcoholism: Clinical and Experimental Research, 27, 49A. Matthews, D.B., Morrow, A.L., Mittleman, G., Ferkin, M., Berry, R.B., Silvers, J.M., Brittingham, C. & Esquivel, A. (2003). Effects of mild footshock stress on anxiety and ethanol drinking in three mouse strains. Alcoholism: Clinical and Experimental Research, 27, 50A. Hamre, K.M., Elberger, A.J., Matthews, D.B. & Du, X. (2003). Examination of the role of the NR1 subunit of the NMDA receptor in ethanol related phenotypes using chimeric mice. Alcoholism: Clinical and Experimental Research, 27, 86A. Silvers, J.M., Goodwin, S.B., Sutter, T.R., Morrow, A.L. & Matthews, D.B. (2003). Chronic intermittent ethanol exposure in adolescent rats produces tolerance to ethanol-induced spatial memory deficits: An investigation of possible molecular mechanisms. Alcoholism: Clinical and Experimental Research, 27, 124A. Berry, R.B., Chandra, D., Homanics, G.E. & Matthews, D.B. (2003). Reduction of GABAA receptor [g]2 subunits reduces ethanol-induced spatial memory impairments in mice. Alcoholism: Clinical and Experimental Research, 27, 130A. Tokunaga, S., Morrow, A.L. & Matthews, D.B. (2003). Allopregnanolone neurogenesis modulates ethanols effect in the hippocampus. Alcoholism: Clinical and Experimental Research, 27, 131A. Hamre, K.M., Wilkinson, S., Matthews, D.B., Goodwin, S., Huang, Y., Sutter, T. & Goldowitz, D. (2004). Microarray analysis of gene expression in the basal ganglia and basal forebrain of a pedigree of ENU-mutagenized mice that exhibit high locomotor activation following ethanol injection. Alcoholism: Clinical and Experimental Research, 28, 9A. Blednov, Y., Weiner, J., Matthews, D., Berry, R., Harrison, N.L., & Homanics, G.E. (2004). Role of the GABAA receptor alpha 1 subunit in alcohol-induced behavioral responses. Alcoholism: Clinical and Experimental Research, 28, 92A. Hamre, K.M., Elberger, A.J., Matthews, D., & Du, X.P. (2004). The NR1 subunit of the NMDA receptor influences ethanol consumption. Alcoholism: Clinical and Experimental Research, 28, 127A. Escher, T., Blistein, J.L., Matthews, D.B. & Mittleman, G. (2004). Pharmacological and behavioral specificity of known and novel drugs to alcohol self-administration in mice. Alcoholism: Clinical and Experimental Research, 28, 15A. Matthews, D.B., Esqvaul, A., Brittingham, C., Silvers, J.R., Berry, R.B. OBuckley, T. & Morrow, A.L. (2004). Acute footshock stress increases ethanol self-administration and plasma corticosterone levels in male, but not female, C57BL/6J mice. Alcoholism: Clinical and Experimental Research, 28, 17A. Hamre, K.M., Matthews, D.B., Rinchik, E., Chesler, E., Goldowitz, D. & Mittleman, G. (2004). Behavioral responses to ethanol or cocaine including locomotor activation and anxiolytic response in ENU-mutagenized mice. Alcoholism: Clinical and Experimental Research, 28, 90A. Goldowitz, D., Matthews D.B., Hamre, K.M. (2004). Initial validation of consomic strains as a valuable tool in studying ethanol withdrawal and self-administration. Alcoholism: Clinical and Experimental Research, 28, 91A. Silvers, J.M, Goodwin, S.B., Sutter, T.R., Morrow, A.L., Kumar, S., Matthews, D.B. (2004). Chronic intermittent ethanol exposure during adolescence produces long-lasting changes in GABAA receptor subunit expression. Alcoholism: Clinical and Experimental Research 28, 93A. Khisti, R.T., VanDoren, M.J., Matthews, D.B., & Morrow A.L. (2004). Allopregnanolone does not mediate ethanol-induced motor incoordination in rats. Alcoholism: Clinical and Experimental Research, 29, 93A. Tokunaga, S., Silvers, J.M., & Matthews, D.B. (2004). Chronic intermittent ethanol exposure produces tolerance to ethanols inhibitory effects of hippocampal pyramidal neural activity. Alcoholism: Clinical and Experimental Research, 28, 138A. Becker, H.C., Fernandes, K.G., Willet, K.A., Lopez. M.F., Goldowitz, D. Matthews, DB & Hamre, K. (2005). Sensitization to locomotor stimulant effects of ethanol and effects on drinking in 22-tnj mutant mice. Alcoholism: Clinical and Experimental Research. Elberger, A.J., Xue, Y., Cardenas, L., Hobson, T., Hamre, K.M., Matthews, D.B. & Goldowitz D. (2005). Brain abnormalities underlying a behavioral ethanol phenotype in the 22TNJ-2 mouse: an INIA-east neurohistology core project. Alcoholism: Clinical and Experimental Research. Matthews, D.B., Hamre, K., & Goldowitz, D. (2005). The use of consomic mouse lines to elucidate genetic influences on ethanol-related phenotypes. Alcoholism: Clinical and Experimental Research. Hamre, K.M., Matthews, D.B., Mittleman, G., & Goldowitz, D. (2005). Screening mutagenized mice for abnormal ethanol responses and ethanol consumption: an update from the TMGC consortium. Society for Neuroscience. Berry, R.B., Silvers, J.M., Freeman, D.A. & Matthews, D.B. (2006). Chronic intermittent ethanol administration during adolescence inhibits normal testicular development in sprague-dawley rats. Alcoholism: Clinical and Experimental Research, 75A. Tinsley, K., Silvers, J.M. & Matthews D.B. (2006). Chronic intermittent exposure to moderate amounts of ethanol during adolescence produces tolerance to the hypnotic effects of ethanol in adult rats: a dose dependent analysis. Alcoholism: Clinical and Experimental Research, 82A. Hamre, K.M., Wilkinson, S., Matthews D.B., Cockcroft, J., Manly, M., Pletcher, M & Goldowitz, D.G. (2006). Mapping 22TNJ, an ENU-induced mutation that exhibits increased locomotor activation following acute ethanol exposure. Alcoholism: Clinical and Experimental Research, 125A. Elberger, A.J., Cardenas, L. Clark, R., Xue, Y., Hobson, T., Hamre, K.M., Matthews, D.B. & Goldowitz, D.G. (2006). Timing of neurosircuitry abnormalities underlying a behavioral ethanol phenotype in 22TNJ mice: An INIA-Stress neurohistology core project. Alcoholism: Clinical and Experimental Research, 125A. Elberger, A.J., Xue, Y., Cardenas, L., Clark, T., Hobson, T., Hamre, K.M., Matthews, D.B., & Goldowitz, D.G. (2006). More brain abnormalities underlying a behavioral ethanol phenotype in 22TNJ mice: An INIA-stress neurohistology core project. Alcoholism: Clinical and Experimental Research, 125A. Booth, A. K., Meyers, A. W., Whelan, J. P., Brittenham, C., & Matthews, D. (2006). Testosterone and Gambling: Do Outcome and Control on a Simulated Gambling Task Affect Salivary Levels? Association for Behavioral and Cognitive Therapies. Chicago, IL. Tinsley, K.L., Miller, A.D., Silvers, J.M., Matthews, D.B., Mittleman, G. & Blaha, C.D. (2006). Dose-dependent hypnotic and neurochemical effects of ethanol resulting from chronic intermittent exposure in adolescent rats. Society for Neuroscience Abstracts. Tokunaga, S., Kumar, S., Silvers, J.M., Morrow, A.L. & Matthews, D.B. (2007). Chronic intermittent ethanol exposure during adolescence alters GABAA and NMDA receptor subunit composition in hippocampus and cortex. Alcoholism: Clinical and Experimental Research, 196A. Tokunaga, S. & Matthews, D.B. (2007). Adolescent Purkinje neurons are less sensitive to alcohols inhibitory effect compared to adult Purkinje neurons. Alcoholism: Clinical and Experimental Research, 206A. Miller, T., Tokunaga, S., Blaha, C.D., Mittleman, G., Matthews, D.B. (2008). Binge-like ethanol exposure during adolescence and young adulthood alters dopamine efflux in the nucleus accumbens to an ethanol challenge. Alcoholism: Clinical and Experimental Research, 35A. Venard, J. & Matthews, D.B. (2008). Preadolescent and adolescent rats are less sensitive to the motor impairing effects of ethanol compared to adult and aged rats. Alcoholism: Clinical and Experimental Research, 91A Matthews, D.B., Arndt, M., Dominguez,C., Venard, J., Keele, N.B., Diaz-Granados, J.L & Miller, J.L. (2008). Differential effect of age but not chronic intermittent ethanol exposure on immobility in the forced swim test in periadolescent and adult rats. Society for Neuroscience Abstracts. Van Skike, C.E. and Matthews, D.B. (2009). PKC gamma expression: Potential mechanism for differential ethanol sensitivity between adolescent and adult rats. Alcoholism: Clinical and Experimental Research, 203A. Chin, V.S, Berry, R.B. and Matthews, D.B. (2009). Adolescent rats are less sensitive than adult rats to the spatial memory impairing effects of acute ethanol. Alcoholism: Clinical and Experimental Research, 216A. Van Skike, C.E., Chin, V.S., Diaz-Granados & Matthews, D.B. (2010). Tolerance to ethanol-induced spatial memory impairments in adolescent rats. Alcoholism: Clinical and Experimental Research, 29A. Chin, V.S., Diaz-Granados, J.L. & Matthews, D.B. (2010). Effects of low dose acute ethanol on spatial memory in adolescent and adult rats. Alcoholism: Clinical and Experimental Research, 30A. Novier, A.K., Van Skike, C.A., Diaz-Granados, J.L. & Matthews, D.B. (2011). Effects of low dose acute ethanol on cognition and movement. Alcoholism: Clinical and Experimental Research, 242A. Van Skike, C.A., Diaz-Granados, J.L & Matthews, D.B. (2011). Adolescent rats may be more predisposed than adults to develop metabolic tolerance after chronic binge alcohol exposure. Alcoholism: Clinical and Experimental Research, 249A. Pang, J.S., Wei, F.W., Diaz-Granados, J.L. & Matthews, D.B. (2011). Presence of a peer significantly decreases amount of liquid poured in a simulated alcohol pouring task in Singaporean college students. Alcoholism: Clinical and Experimental Research, 79A. Novier, A., Van Skike, C.E., Diaz-Dranados, J.L., Mittleman, G. & Matthews, D.B. (2012). Acute alcohol produces profound ataxic and cognitive effects in aged animals. Alcoholism: Clinical and Experimental Research, 79A Van Skike, C.E., Novier, A., Diaz-Granados, J.L. & Matthews, D.B. (2012). Exercise does not affect Morris water maze acquisition or ethanol-induced cognitive impairments in adolescent or adult male rats. Alcoholism: Clinical and Experimental Research Novier, A., Ornelas, L.C., Van Skike, C.E., Diaz-Granados, J.L. & Matthews, D.B. (2013). The effects of chronic intermittent ethanol and/or acute ethanol on motor and cognitive performance. Alcoholism: Clinical and Experimental Research, 79A Van Skike, C.E., Diaz-Granados, J.L. & Matthews, D.B. (2013). Chronic intermittent ethanol exposure yields persistent increases in anxiety and altered receptor subunit expression in adolescent and adult male rats. Alcoholism: Clinical and Experimental Research Orneals, L.C., Novier, A., Van Skike, C.E., Diaz-Granados, J.L. & Matthews, D.B. (2014). The effects of acute ethanol on motor impairments in adolescents, adult and aged rats. Alcoholism: Clinical and Experimental Research, 239A. Novier, A., Orneals, L.C., Van Skike, C.E., Diaz-Granados, J.L. & Matthews, D.B. (2014). Baylor longitudinal study: The effects of chronic intermittent ethanol during adolescences and acute ethanol on motor and cognitive performance. Alcoholism: Clinical and Experimental Research, 240A. Novier, A., Orneals, L.C., Diaz-Granados, J.L. & Matthews, D.B. (2015). Age-related differences in ethanol withdrawal, withdrawal-induced anxiety, cognition and response to allopregnanolone. Alcoholism: Clinical and Experimental Research, 56A. Matthews, D.B., Bakalars, C.A., Hasenberg, W.G., Watson, M.R. & Mittleman, G. (2016). Gender and AUDIT score significantly interact to effect fluid pour in a simulated alcohol free pour task. Alcoholism: Clinical and Experimental Research, 96A. Matthews, D.B., Watson, M.R. & Mittleman, G. (2017). Understanding the impact of chronic intermittent ethanol exposure in aged, adult and adolescent rats. Alcoholism: Clinical and Experimental Research, 33A. Matthews, D.B., Bakalars, C.A., Watson, M.R., Hasenberg, W.G., Dayib, N., Ackley, B & Mittleman, G. (2017). Rescuing the overpouring effect: The impact of perceived drinking situation on fluid poured in a simulated alcohol free pour task. Alcoholism: Clinical and Experimental Research, 94A. Matthews, D.B., Watson, M.R., Kastner, K., James, K., Schneider, A. & Mittleman, G. (2018). The effect of chronic intermittent ethanol exposure across the lifespan in rats. Alcoholism: Clinical and Experimental Research, 167A. Matthews, D.B., Watson, M.R., Duce, L., Ackley, B., Brock, E., Schneider, A., Bayer, R, & George, K. (2018). Relationship between self-report heavy alcohol use, fluid poured and internet pornography use in college students. Alcoholism: Clinical and Experimental Research, 202A. Watson, M.R., James, K., Schneider, A., Kastner, A., Scaletty, S., Benes, A., Szenay, S., Turgeson, B., Mittleman, G. & Matthews, D.B. (2019). Increased hypothermia in aged rats following acute ethanol exposure. Alcoholism: Clinical and Experimental Research, 222A. Matthews, D.B., Tillotson, V.L., Scallety, S., Lyman-Gingerich, J., Zamudio, P.A., Okas, M. & Woodward, J. (2021). F639A mutation does not alter spatial memory deficits produced by acute ethanol administration. Alcoholism: Clinical and Experimental Research, 80A. Matthews, D.B., Scaletty, S., Trapp, S., Tillotson, V.L., Bossany, H., Shang, P., Choi, D.S. (2021). Brief chronic intermittent ethanol exposures reduces behavioral flexibility in aged rats but not adult rats. Alcoholism: Clinical and Experimental Research, 101A. Rossmann, G., Petersilka, Q., Oliver, P., Shult, C., Wieden, T., Matthews, D.B. (2022). Aged male rats show increased motoric activity to low-dose ethanol compared to adult and adolescent male rats. Alcoholism: Clinical and Experimental Research, 188A. Sharma, P., Holland, A., Pazdernik, V., Geske, J., Patten, C.A., Matthews, D.B., Sharma, S., Rossmann, G., Kolla, B., Breitinger, S.A., Frye, M.A. & Ozerdem, A. (2022). Female Gender and Pre-COVID Depressive Symptoms Associated with COVID-19 Binge Drinking. Annual meeting of National Network of Depressive Centers. Matthews, D.B., Rossmann, G., Matthews, S.J., Shult, C., Turunen, A., Petersilka, Q., Oliver, P., Zank, A. & Sharma, P. (2023). Aged male rats have increased movement but lack an anxiolytic effect to 1.0 g/kg ethanol: Comparisons to adult and adolescent male rats. Alcohol: Clinical and Experimental Research, 47(S1), 181. Matthews, D.B., Wieden, T., Turunen, A., Shult, C., Sharma, P. (2023). Effect of chronic intermittent ethanol exposure and age on PKC-isoform expression in the cerebellum. Alcohol: Clinical and Experimental Research, 47(S1), 182. Matthews, D.B., Garscia, A., Zank, A., Hartwig, J., Kerr, E., Stumo, S & Crippen, A. (2024). The impact of sex and age on the effect of acute alcohol exposure across the lifespan in rats. Alcohol: Clinical and Experimental Research. INVITED COLLOQUIA Miami University--Department of Psychology, September 1995. Miami University--Department of Zoology, February 1996. University of North Carolina--Skipper-Bowles Center for Alcohol Studies, Medical School, September 1996. Yale University--Department of Psychology, September 1996. University of North Carolina--Curriculum in Neurobiology, September 1997. Scientific American (Sigma Xi) Research Triangle Park, North Carolina, May 1998. University of North Carolina Department of Psychology: Experimental and Biological Psychology Seminar, September 1998. Texas Christian University Department of Psychology, February 1999. University of Memphis Department of Psychology, March 1999. Baylor University Department of Psychology and Neuroscience, April 2001. University of Tennessee Health Science Center Neuroscience, October 2001. Delta State University Department of Biology, November 2002. University of North Carolina -- Skipper-Bowles Center for Alcohol Studies, Medical School, March 2003. Binghamton University Department of Psychology, April 2004. Medical University of South Carolina Alcohol Research Center, April 2004. Baylor University Department of Psychology and Neuroscience, November 2006. National University of Singapore, Singapore, Division of Psychology, Oct 2007. Nanyang Technological University, Singapore, Division of Psychology, Oct 2007. Texas Tech University, Health Sciences Center, Pharmacology and Neuroscience, March 2008. University of Texas at Austin, Waggoneer Center for Alcohol and Addictions Studies, April 2008. National University of Singapore, Division of Psychology, March 2010. Singapore Society for Neuroscience, March, 2010. National University of Vietnam, May, 2010. Kansas State University, Department of Psychology, February 2012. Singapore Psychological Society, October 2013. University of Wisconsin Eau Claire, Department of Psychology, January 2014. Ball State University, Department of Psychology, January 2015. IUPUI, Addictions Research Group, January 2015. 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